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Blood Type B Agglutination

Blood typing is a fast and easy way to ensure that you receive the right kind of blood during. In typing for the abo antigens rbcs are mixed on a slide with antisera to the a or b blood group antigens.

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Blood types are indicated by both the abo and rh antigens present.

Blood type b agglutination. Return to rh system. Individuals with type a blood without any prior exposure to incompatible blood have preformed antibodies to the b antigen circulating in their blood plasma. The corresponding antigen and antibody are never found in the same individual since when mixed they form antigen antibody complexes effectively agglutinating the blood.

Antibodies agglutinins for the antigens a and b exist in the plasma and these are termed anti a and anti b. If the antigen is present on the cells they agglutinate forming a visible clump on the slide. If your blood agglutinates in anti b you have the b antigen and are type b.

Thus there are four main blood groups which differ with respect to two antigens a and b in the red blood cells and two isohemagglutinins anti a and anti b in the serum. If the blood cells clump agglutinate the antibody has bound to the appropriate antigen on the cells. Hemagglutination is used in blood typing agglutination reactions are routinely performed to type red blood cells.

Thus in humans type o has neither antigen but both agglutinins type a has a antigen and anti b agglutinin type b has b antigen and anti a agglutinin and type ab has both antigens but neither agglutinin. Blood typing is done prior to a blood transfusion or when classifying a person s blood for donation. These antibodies referred to as anti b antibodies will cause agglutination and hemolysis if they ever encounter erythrocytes with b antigens.

Your blood type matches whatever antibody caused agglutination.

Rosh Review Type A Type B Hematology Medicine

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